
In season one we are introduced to the local community through the eyes of young nurse Jenny Lee as she lives and works as a midwife alongside the Nuns of the Order of St. Raymond of Nonnatus in the deprived Poplar district of London's desperately poor East End in the 1950s.

Jenny Lee start her midwife career at Nonnatus House in London. She is surprised to find that it is a nursing convent and not a hospital. Her first case is a woman pregnant for the 25th time!

A new girl arrives Nonnatus House and finds it hard to earn the respect of Sister Evangelina. Jenny sees an unfamiliar darker side of life following an encounter with a runaway.

Jenny does some district nursing to extend her community practice experience and befriends an old soldier with awful leg ulcers. Trixie and Cynthia enrol Winnie Lawson as a new patient.

A baby girl is snatched from her pram and the local community unites for the search. Cynthia sees another sort of loss as she tends to soon-to-be parents David and Margaret.