01. The Bubbler
The Bubbler kidnaps the Shah of Shish-Ka-Bob and it's up to the Impossibles to rescue the Shah.
02. The Spinner
The Spinner steals a $1,000,000 tiara.
03. The Perilous Paper Doll
The Paper Doll Man has stolen a top secret plan and is out to steal the second part.
04. Beamatron
Beamatron steals a priceless painting from a ship.
05. The Burrower
The Burrower uses his burrowing machine to steal half a million dollars from the bank and dig ten miles down to his lair.
06. Timeatron
Timeatron uses his time cabinet to bring villains from the past to pillage for him.
07. Smogula
Smogula freezes the Impossibles and seals them within a cave, so they will not interfere with his plans to conquer Empire City.
08. The Sinister Speck
The Speck uses a formula to shrink himself in order to photograph top secret plans.
09. Fero, the Fiendish Fiddler
To get the Impossibles out of the way, Fero uses his fiddle to transport them to different planets.
10. Mother Gruesome
Mother Gruesome invents a machine that brings villainous storybook characters out of their stories to help her with her crimes.
11. Televisatron
Televisatron transports the Impossibles to different television shows.
12. The Diabolical Dauber
The Dauber uses a special brush where anything he paints becomes real.
13. Aquator
Aquator has stolen a secret formula from a scientist who is friends with Big D and shrinks himself to microscopic size in order to get all the microscopic creatures to become large.
14. The Wretched Professor Stretch
Professor Stretch causes havoc with his elastic abilities.
15. The Devilish Dragster
The Dragster has stolen a valuable item.
16. The Return of the Spinner
The Spinner returns and steals a priceless pooch.
17. Satanic Surfer
The Surfer takes pictures of a top secret submarine.
18. The Puzzler
The Puzzler steals top secret documents.
19. The Scheming Spraysol
Spraysol steals top secret documents.
20. The Scurrilous Sculptor
The Sculptor turns people into statues.
21. The Artful Archer
The Archer steals a priceless violin and a million dollars.
22. The Insidious Inflator
The Inflator creates giant balloon monsters to help him commit crimes.
23. The Dastardly Diamond Dazzler
The Diamond Dazzler steals a precious diamond in order to awaken the genie within.
24. The Return of the Perilous Paperman
The Paper Doll Man returns and causes trouble.
25. Cronella Critch the Tricky Witch
A witch named Cronella Critch robs a charity for orphans party.
26. The Terrible Twister
The Twister is stealing precious jewels.
27. Professor Stretch Bounces Back
Professor Stretch returns and creates a rubber monster to help him.
28. The Terrifying Tapper
The Tapper transmits himself over phone lines.
29. The Anxious Angler
The Angler steals secret space research.
30. The Rascally Ringmaster
The Ringmaster puts on a circus and robs from those who attend.
31. Billy the Kidder
Billy the Kidder is a cowboy who rides a robotic horse and plans to rob the U.S. Mint.
32. The Fiendish Dr. Futuro
Dr. Futuro comes from the 40th century to the twentieth century to steal a million dollar gold brick.
33. The Crafty Clutcher
The Clutcher uses an invention that brings his gloves to life.
34. The Infamous Mr. Instant
Mr. Instant uses his insta-gun that can make anything in an instant.
35. The Bizarre Batter
The Batter kidnaps a baseball star and holds him for ransom.
36. The Not So Nice Mr. Ice
Mr. Ice and his henchman Freezer Freezer freeze the city in order to take it over.